Sleep spindles predict stress-related increases in sleep disturbances.

摘要: Background and Aim: Predisposing factors place certain individuals at higher risk for insomnia, especially in the presence of precipitating conditions such as stressful life events. Sleep spindles have been shown to play an important role preservation sleep continuity. Lower spindle density might thus constitute objective predisposing factor reactivity stress. The aim this study was therefore evaluate relationship between baseline prospective change insomnia symptoms response a standardized academic stressor. Methods: 12 healthy students had polysomnography (PSG) recording during period lower stress beginning semester, along with assessment complaints using Insomnia Severity Index (ISI). They completed second ISI end coinciding week prior final examinations Spindle density, amplitude, duration frequency, well sigma power were computed from C4-O2 electroencephalography (EEG) derivation stages N2-N3 non-rapid-eye-movement (NREM) sleep, across whole night each NREM period. To test changes stress, measurements correlated semester. Results: (as amplitude power), particularly first period, negatively (p < 0.05). Conclusion: activity, night, prospectively predicted larger increases This result indicates that individual differences activity contribute differential vulnerability disturbances face factors.