Triacylglycerol and wax ester-accumulating machinery in prokaryotes.

摘要: Gram negative bacteria as well positive actinobacteria possess the ability to accumulate variable amounts of wax esters (WE) and/or triacylglycerols (TAG) under nitrogen limiting conditions. In recent years many advances have been made obtain insight into neutral lipid biosynthesis and accumulation in prokaryotes. The clinical industrial relevance bacterial WE/TAG significantly promoted basic applied research this field. integrated omic studies functional characterization diverse genes are contributing unravel composition WE/TAG-accumulating machinery bacteria. This will be a valuable data for designing new drugs against with importance, such Mycobacterium tuberculosis, or transferring optimizing hosts naturally unable produce lipids, Escherichia coli. article, investigations addressing storage prokaryotes presented. A comprehensive view current knowledge on different genes/proteins involved is included.