Progress and challenge in development of biotherapeutics targeting MET receptor for treatment of advanced cancer.

作者: Hang-Ping Yao , Rachel Hudson , Ming-Hai Wang

DOI: 10.1016/J.BBCAN.2020.188425

关键词:

摘要: … Second, the action of SHR-A1403 in vivo is relatively broad. Xenograft tumors mediated by … sensitive to SHR-A1403 with variable but significant inhibition [40,97,98]. Third, SHR-A1403-…

参考文章(95)
Muscatelli F, Breathnach R, Mattei Mg, Ronsin C, A novel putative receptor protein tyrosine kinase of the met family Oncogene. ,vol. 8, pp. 1195- 1202 ,(1993)
Anna Hultberg, Virginia Morello, Leander Huyghe, Natalie De Jonge, Christophe Blanchetot, Valérie Hanssens, Gitte De Boeck, Karen Silence, Els Festjens, Raimond Heukers, Benjamin Roux, Fabienne Lamballe, Christophe Ginestier, Emmanuelle Charafe-Jauffret, Flavio Maina, Peter Brouckaert, Michael Saunders, Alain Thibault, Torsten Dreier, Hans de Haard, Paolo Michieli, Depleting MET-Expressing Tumor Cells by ADCC Provides a Therapeutic Advantage over Inhibiting HGF/MET Signaling Cancer Research. ,vol. 75, pp. 3373- 3383 ,(2015) , 10.1158/0008-5472.CAN-15-0356
R Castoldi, V Ecker, L Wiehle, M Majety, R Busl-Schuller, M Asmussen, A Nopora, U Jucknischke, F Osl, S Kobold, W Scheuer, M Venturi, C Klein, G Niederfellner, C Sustmann, A novel bispecific EGFR/Met antibody blocks tumor-promoting phenotypic effects induced by resistance to EGFR inhibition and has potent antitumor activity Oncogene. ,vol. 32, pp. 5593- 5601 ,(2013) , 10.1038/ONC.2013.245
Alberto Bardelli, Paola Longati, Tracy A. Williams, Silvia Benvenuti, Paolo M. Comoglio, A Peptide Representing the Carboxyl-terminal Tail of the Met Receptor Inhibits Kinase Activity and Invasive Growth Journal of Biological Chemistry. ,vol. 274, pp. 29274- 29281 ,(1999) , 10.1074/JBC.274.41.29274
J M Lee, B Kim, S B Lee, Y Jeong, Y M Oh, Y-J Song, S Jung, J Choi, S Lee, K H Cheong, D U Kim, H W Park, Y K Han, G W Kim, H Choi, P H Song, K A Kim, Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met-targeting antibody Oncogene. ,vol. 33, pp. 34- 43 ,(2014) , 10.1038/ONC.2012.551
Koji Tsuta, Yoshiki Kozu, Takahiro Mimae, Akihiko Yoshida, Takashi Kohno, Ikuo Sekine, Tomohide Tamura, Hisao Asamura, Koh Furuta, Hitoshi Tsuda, c-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas. Journal of Thoracic Oncology. ,vol. 7, pp. 331- 339 ,(2012) , 10.1097/JTO.0B013E318241655F
Michael Dean, Morag Park, Michelle M. Le Beau, Terry S. Robins, Manuel O. Diaz, Janet D. Rowley, Donald G. Blair, George F. Vande Woude, The human met oncogene is related to the tyrosine kinase oncogenes Nature. ,vol. 318, pp. 385- 388 ,(1985) , 10.1038/318385A0
Dineli Wickramasinghe, Monica Kong-Beltran, Met activation and receptor dimerization in cancer: a role for the Sema domain. Cell Cycle. ,vol. 4, pp. 683- 685 ,(2005) , 10.4161/CC.4.5.1688
Ling Liu, Wei Zeng, Mark A. Wortinger, S. Betty Yan, Paul Cornwell, Victoria L. Peek, Jennifer R. Stephens, Jonathan W. Tetreault, Jinqi Xia, Jason R. Manro, Kelly M. Credille, Darryl W. Ballard, Patricia Brown-Augsburger, Volker Wacheck, Chi-Kin Chow, Lihua Huang, Yong Wang, Irene Denning, Julian Davies, Ying Tang, Peter Vaillancourt, Jirong Lu, LY2875358, a Neutralizing and Internalizing Anti-MET Bivalent Antibody, Inhibits HGF-Dependent and HGF-Independent MET Activation and Tumor Growth Clinical Cancer Research. ,vol. 20, pp. 6059- 6070 ,(2014) , 10.1158/1078-0432.CCR-14-0543
Wen-Ying Lee, Helen H.W. Chen, Nan-Haw Chow, Wu-Chou Su, Pin-Wen Lin, How-Ran Guo, Prognostic Significance of Co-expression of RON and MET Receptors in Node-Negative Breast Cancer Patients Clinical Cancer Research. ,vol. 11, pp. 2222- 2228 ,(2005) , 10.1158/1078-0432.CCR-04-1761