摘要: Next-generation sequencing (also known as massively parallel sequencing) technologies are revolutionising our ability to characterise cancers at the genomic, transcriptomic and epigenetic levels. Cataloguing all mutations, copy number aberrations somatic rearrangements in an entire cancer genome base pair resolution can now be performed a matter of weeks. Furthermore, used means for unbiased analysis mRNAs, small RNAs noncoding RNAs, genome-wide methylation assays high-throughput chromatin immunoprecipitation assays. Here, I discuss potential impact this technology on breast research challenges that come with technological breakthrough.
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