A model of erythropoiesis in adults with sufficient iron availability

摘要: In this paper we present a model for erythropoiesis under the basic assumption that sufficient iron availability is guaranteed. An extension of including sub-model dynamics in body topic research efforts. The gives excellent results number important situations: recovery red blood cell mass after donation, adaptation cells to changes altitude residence and, most important, reaction different administration regimens stimulating agents, as instance case pre-surgical Epoetin-α. simulation concerning last item show choosing an appropriate regimen can reduce total amount administered drug considerably. core consists structured population equations populations which are considered. A key feature incorporation neocytolysis.