Stem Cells in Neurotoxicology/Developmental Neurotoxicology: Current Scenario and Future Prospects.

摘要: Stem cell biology has played a pivotal role in the field of disease modeling, regenerative medicine, and tissue engineering. The scope stem research been further extended to address issues associated with toxicity biosafety. However, its neurotoxicity (NT) emerging developmental (DNT) is somewhat underrepresented needs thorough investigation. Several challenges have hindered progress NT DNT studies, there dire need for human-specific high-throughput vitro system(s) as tool better predictivity, reliability, reproducibility. unique proliferation pluripotency cells makes them tremendous resource human material, allowing prediction drug metabolic effects chemicals. Recognizing growing importance application biology, this review article, we provide diversified approaches which can be effectively applied studies an update recent made so far. We futuristic approach towards novel cell-based strategies testing. discussed current technologies, induced pluripotent cells, three-dimensional (3D) cultures cell-derived organs studies.