Disarray of glomerular and tubular cell adhesion molecules in the course of experimental Bothrops moojeni envenomation
作者： Carla Beatriz Collares-Buzato , Maria Alice da Cruz-Höfling
DOI: 10.1016/J.TOXICON.2013.11.013
关键词:
摘要: In this study, we show that administration of Bothrops moojeni venom in rats induces a general disturbance the distribution and content tight junctional protein ZO-1, cell-matrix receptor beta 1 integrin, cytoskeletal proteins, vinculin F-actin, extracellular matrix component laminin renal corpuscles cortical nephron tubules. These findings suggest cell-cell adhesion proteins may be molecular targets B. moojeni-induced kidney injury.
sci-hub.se 参考文章(29)
V. Cattell, Focal mesangial proliferative glomerulonephritis in the rat caused by Habu snake venom: the role of platelets. British journal of experimental pathology. ,vol. 60, pp. 201- 208 ,(1979)
Emmanuel A. Burdmann, Euthymia B. A. Prado, Orlando C. O. Barreto, Regina C. Abdulkader, Marcello Marcondes, Viktoria Woronik, Luiz B. Saldanha, Snakebite-induced acute renal failure: an experimental model American Journal of Tropical Medicine and Hygiene. ,vol. 48, pp. 82- 88 ,(1993) , 10.4269/AJTMH.1993.48.82
P.S.F Barbosa, A Havt, P.E.G Facó, T.M Sousa, I.S.A.M Bezerra, M.C Fonteles, M.H Toyama, S Marangoni, J.C Novello, H.S.A Monteiro, Renal toxicity of Bothrops moojeni snake venom and its main myotoxins Toxicon. ,vol. 40, pp. 1427- 1435 ,(2002) , 10.1016/S0041-0101(02)00156-3
Giselle Pidde Queiroz, Lucas Alves Pessoa, Fernanda C.V. Portaro, Maria de Fátima D. Furtado, Denise V. Tambourgi, Interspecific variation in venom composition and toxicity of Brazilian snakes from Bothrops genus. Toxicon. ,vol. 52, pp. 842- 851 ,(2008) , 10.1016/J.TOXICON.2008.10.002
Marina T. Assakura, Antonia P. Reichl, Maria Cristina A. Asperti, Fajga R. Mandelbaum, Isolation of the major proteolytic enzyme from the venom of the snake Bothrops moojeni (caissaca). Toxicon. ,vol. 23, pp. 691- 706 ,(1985) , 10.1016/0041-0101(85)90374-5
Carla B. Collares-Buzato, Mark A. Jepson, Nicholas L. Simmons, Barry H. Hirst, Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia European Journal of Cell Biology. ,vol. 76, pp. 85- 92 ,(1998) , 10.1016/S0171-9335(98)80020-4
Daniela C.S. Damico, Juliana Minardi Nascimento, Bruno Lomonte, Luis A. Ponce-Soto, Paulo P. Joazeiro, José Camillo Novello, Sérgio Marangoni, Carla B. Collares-Buzato, Cytotoxicity of Lachesis muta muta snake (bushmaster) venom and its purified basic phospholipase A2 (LmTX-I) in cultured cells. Toxicon. ,vol. 49, pp. 678- 692 ,(2007) , 10.1016/J.TOXICON.2006.11.014
Carla B Collares-Buzato, Luciana de Paula Le Sueur, Maria Alice da Cruz-Höfling, None, Impairment of the cell-to-matrix adhesion and cytotoxicity induced by Bothrops moojeni snake venom in cultured renal tubular epithelia. Toxicology and Applied Pharmacology. ,vol. 181, pp. 124- 132 ,(2002) , 10.1006/TAAP.2002.9404
E PEIXOTO, C COLLARESBUZATO, Modulation of the epithelial barrier by dexamethasone and prolactin in cultured Madin-Darby canine kidney (MDCK) cells. Cell Biology International. ,vol. 30, pp. 101- 113 ,(2006) , 10.1016/J.CELLBI.2005.08.004
Andrana K. Calgarotto, Daniela C.S. Damico, L.A. Ponce-Soto, Paulo A. Baldasso, Saulo L. Da Silva, Gustavo H.M.F Souza, Marcos N. Eberlin, Sergio Marangoni, Biological and biochemical characterization of new basic phospholipase A2 BmTX-I isolated from Bothrops moojeni snake venom Toxicon. ,vol. 51, pp. 1509- 1519 ,(2008) , 10.1016/J.TOXICON.2008.03.030