DESIGN OF RIBONUCLEASE MIMICS FOR SEQUENCE SPECIFIC CLEAVAGE OF RNA
作者： Vladimir Silnikov , Guy Zuber , Valentin Vlassov , Richard Giege , Jean-Paul Behr
DOI: 10.1080/10426509608046252
关键词:
摘要: Abstract. Hydrolysis of RNA by imidazole conjugates capable binding to have been investigated. Spermine-imidazole conjugate in the presence buffer cleaves at single-stranded pyrimidine-purine sequences. Oligonucleotides with a diimidazole construction terminal phosphate cleave tRNA target vicinity complementary
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