Utilization of Fish Oil for the Prevention and Treatment of Traumatic Brain Injury

摘要: Traumatic brain injury (TBI), with its diverse heterogeneity and prolonged secondary pathogenesis, remains a clinical challenge. Clinical studies thus far have failed to identify an effective treatment strategy when combination of targets controlling aspects neuroprotection, neuroinflammation, neuroregeneration is needed. Omega-3 fatty acids (n–3FA) offer the advantage this approach. Although further trial research needed, there growing body strong preclinical evidence experience which suggests that benefits may be possible from aggressively adding substantial amounts n–3FA optimize nutritional foundation TBI, concussion, postconcussion syndrome patients. Early optimal doses n–3FA, even in prehospital or emergency department setting has potential improve outcomes potentially devastating public health problem. With unsurpassed safety tolerability, should considered mainstream, conventional medicine, if medicine can overcome inherent bias against nutritional, nonpharmacologic therapies.