Quantitative detection of HIV-1 drug resistance mutations by automated DNA sequencing.
作者： B. A. Larder , A. Kohli , P. Kellam , S. D. Kemp , M. Kronick
DOI: 10.1038/365671A0
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摘要: … eral bloodmononuclearcells) we firstly made mixtures of HIV-1 reverse transcriptase (RT) DNA cloned into M13 bacteriophage. We mixed defined amounts of each clone, which …
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