Prevalence and intensity of Schistosoma haematobium infection among schoolchildren in central Zambia before and after mass treatment with a single dose of praziquantel

摘要: Introduction: Urinary schistosomiasis caused by Schistosoma haematobium is common in some parts of Lusaka Province, Zambia, where water contact activity high and sanitation poor. We conducted a longitudinal study Ng'ombe Compound Lusaka, between 2007 2015, to observe the prevalence intensity S. infection among community primary school children, before after receiving single dose praziquantel. Materials Methods: A total 975 (445 females 530 males) pupils, aged 9–16 years, were tested for at baseline. After mass treatment with praziquantel 2010, 1570 pupils (785 785 males), 9–15 examined eggs, from 2011 2015. Results: At baseline, 279 out children infected, light infections constituting 84.9% 15.1% classified as heavy infection. praziquantel, rate dropped, slightly, 20.3% (63 310) 2011. However, it increased following years up 38% (133 350) rates higher males than females. The average number cases 24.3% (120 494) treatment, reducing 75.7% (374 494). Conclusion: This revealed that was not sufficient significantly reduce transmission schistosomiasis. Further studies will need evaluate whether multiple treatments be more therapeutically effective limiting future incidences.