Bifurcations and enhancement of neuronal firing induced by negative feedback

摘要: Bifurcations and enhancement of neuronal firing induced by negative feedback from an inhibitory autapse are investigated. A slow model that can exhibit dynamics similar to the a rat interneuron is considered. Compared with Morris–Lecar (ML) without autapse, enlargement parameter region activities in ML be identified 1-parameter 2-parameter bifurcations shift inverse Hopf bifurcation point. The right point resting state high membrane potential level causes change autapse. This shows enhance well interpreted dynamic responses impulse current. In addition, many complex such as coexisting behaviors codimension-2 also induced, relationship between physiological concept, depolarization block, phenomenon which neuron enters when it receives excessive excitatory or depolarizing current, discussed. results provide novel viewpoint enhances rather than suppresses near point, important example showing play positive role nonlinear dynamics.