Thrombopoietin protects against doxorubicin-induced cardiomyopathy, improves cardiac function, and reversely alters specific signalling networks

作者: Kathy Yuen-Yee Chan , Ping Xiang , Ligang Zhou , Karen Li , Pak-Cheung Ng

DOI: 10.1093/EURJHF/HFR001

关键词:

摘要: … chemokine signalling, focal adhesion, and haematopoietic cell lineage for up-regulated targets, whereas targets involved in cardiomyopathy and calcium signalling pathways were down…

参考文章(33)
Nikos Werner, Sonja Kosiol, Tobias Schiegl, Patrick Ahlers, Katrin Walenta, Andreas Link, Michael Böhm, Georg Nickenig, Circulating endothelial progenitor cells and cardiovascular outcomes. The New England Journal of Medicine. ,vol. 353, pp. 999- 1007 ,(2005) , 10.1056/NEJMOA043814
Ankur Saxena, Jason E. Fish, Michael D. White, Sangho Yu, James W.P. Smyth, Robin M. Shaw, J. Michael DiMaio, Deepak Srivastava, Stromal Cell–Derived Factor-1α Is Cardioprotective After Myocardial Infarction Circulation. ,vol. 117, pp. 2224- 2231 ,(2008) , 10.1161/CIRCULATIONAHA.107.694992
Marcin Majka, Janina Ratajczak, Gaston Villaire, Krystyna Kubiczek, Leah A Marquez, Anna Janowska-Wieczorek, Mariusz Z Ratajczak, Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT, and STAT proteins in normal human CD34+ cells, megakaryocytes, and platelets. Experimental Hematology. ,vol. 30, pp. 751- 760 ,(2002) , 10.1016/S0301-472X(02)00810-X
A.-M. Engelbrecht, B. Ellis, Apoptosis is mediated by cytosolic phospholipase A2 during simulated ischaemia/reperfusion-induced injury in neonatal cardiac myocytes. Prostaglandins Leukotrienes and Essential Fatty Acids. ,vol. 77, pp. 37- 43 ,(2007) , 10.1016/J.PLEFA.2007.06.002
Mervin C Yoder, Laura E Mead, Daniel Prater, Theresa R Krier, Karim N Mroueh, Fang Li, Rachel Krasich, Constance J Temm, Josef T Prchal, David A Ingram, None, Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals Blood. ,vol. 109, pp. 1801- 1809 ,(2007) , 10.1182/BLOOD-2006-08-043471
Catherine Pavoine, Nicole Defer, The cardiac β2-adrenergic signalling a new role for the cPLA2 Cellular Signalling. ,vol. 17, pp. 141- 152 ,(2005) , 10.1016/J.CELLSIG.2004.09.001
Ping Xiang, Hai Yan Deng, Karen Li, Guo-Ying Huang, Yuan Chen, Liu Tu, Pak Cheung Ng, Nga Hin Pong, Hailu Zhao, Lei Zhang, Rita Yn Tz Sung, Dexrazoxane protects against doxorubicin-induced cardiomyopathy: upregulation of Akt and Erk phosphorylation in a rat model Cancer Chemotherapy and Pharmacology. ,vol. 63, pp. 343- 349 ,(2009) , 10.1007/S00280-008-0744-4
Xiaoming Yi, Raffi Bekeredjian, Nicholas J. DeFilippis, Zakir Siddiquee, Eduardo Fernandez, Ralph V. Shohet, Transcriptional analysis of doxorubicin-induced cardiotoxicity American Journal of Physiology-heart and Circulatory Physiology. ,vol. 290, ,(2006) , 10.1152/AJPHEART.00832.2005
Marc-Michael Zaruba, Hans Diogenes Theiss, Markus Vallaster, Ursula Mehl, Stefan Brunner, Robert David, Rebekka Fischer, Lisa Krieg, Eva Hirsch, Bruno Huber, Petra Nathan, Lars Israel, Axel Imhof, Nadja Herbach, Gerald Assmann, Ruediger Wanke, Josef Mueller-Hoecker, Gerhard Steinbeck, Wolfgang-Michael Franz, Synergy between CD26/DPP-IV inhibition and G-CSF improves cardiac function after acute myocardial infarction Cell Stem Cell. ,vol. 4, pp. 313- 323 ,(2009) , 10.1016/J.STEM.2009.02.013
Syed Haq, Heiko Kilter, Ashour Michael, Jingzang Tao, Eileen O'Leary, Xio Ming Sun, Brian Walters, Kausik Bhattacharya, Xin Chen, Lei Cui, Michele Andreucci, Anthony Rosenzweig, J. Luis Guerrero, Richard Patten, Ronglih Liao, Jeffery Molkentin, Michael Picard, Joseph V. Bonventre, Thomas Force, Deletion of cytosolic phospholipase A2 promotes striated muscle growth. Nature Medicine. ,vol. 9, pp. 944- 951 ,(2003) , 10.1038/NM891