Pouchitis after ileal pouch‐anal anastomosis in ulcerative colitis: Diagnosis, management, risk factors, and incidence

摘要: Restorative proctocolectomy with ileal pouch-anal anastomosis has been the surgical treatment of choice for patients ulcerative colitis who require surgery. Quality life after this procedure is satisfactory in most cases; however, pouchitis a troublesome condition involving inflammation pouch. When patient presents symptoms pouchitis, such as increased bowel movements, mucous and/or bloody exudates, abdominal cramps, and fever, endoscopy essential precise diagnosis. The proximal ileum rectal cuff, well pouch, should be endoscopically observed. reported incidence ranges from 14% to 59%, antibiotic therapy primary acute pouchitis. Chronic includes antibiotic-dependent refractory Intensive including antitumor necrosis factor antibodies steroids may necessary antibiotic-refractory pouch failure occur despite intensive treatment. Reported risk factors development include presence extraintestinal manifestations, sclerosing cholangitis, non-smoking, postoperative non-steroidal anti-inflammatory drug usage. In present review, we focus on diagnosis, endoscopic features, management, incidence, underwent anastomosis.