High coronary artery calcium scores pose an extremely elevated risk for hard events

作者: Roberto Wayhs , Allan Zelinger , Paolo Raggi

DOI: 10.1016/S0735-1097(01)01737-5

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摘要: Abstract Objectives We sought to assess the natural history of a cohort asymptomatic individuals with very high (≥1,000) calcium scores (CSs) on screening electron beam tomography (EBT) not submitted further testing after initial scan. also compared outcome our prospective that historical controls severe abnormalities myocardial perfusion imaging (MPI). Background Coronary detected EBT has been shown correlate total plaque burden. However, there is still controversy as prognostic significance calcium, some investigators believe presence coronary calcification may stabilize atherosclerotic plaque. Methods Ninety-eight subjects (mean age: 62 ± 10) were followed for an average 17 11 months (range: 4 36 months) undergoing occurrence hard events (HCEs), defined infarction or death. All patients had CS ≥1,000, and in none did results lead invasive non-invasive testing. Results During follow-up period, 35 (36%) suffered HCE. recorded first 28 follow-up. Subjects HCEs higher CSs than suffering (1,561 270 vs. 1,199 200, p Conclusions A person portends risk HCE short term. This appears be greater associated abnormality MPI.

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