作者: Russell J. Molyneux , Kip E. Panter
DOI: 10.1016/S1099-4831(09)06703-0
关键词:
摘要: Abstract Plant poisonings are a major problem for livestock producers. The majority of these episodes due to alkaloid constituents, encompassing numerous plant species. Reviews the have traditionally been organized on basis families and genera, less frequently by animal species and/or organs affected. This review is structural classes alkaloids responsible, emphasizing actual toxin mechanism action, correlating similar mechanisms toxicity across disparate species, together with structure–activity relationships. Although worldwide in nature, this chapter focuses situations within North America, but covers analogous other parts world when same class family involved. Disease states include acute chronic poisonings, hepatotoxicity, pulmonary toxicity, teratogenicity, neurotoxicity, cardiotoxicity, reproductive problems, failure thrive. potential biomedical applications some discussed. Specific dealt pyrrolidine, piperidine, bipiperidine, pyridine, polyhydroxy indolizidine, quinolizidine, tropane, pyrrolizidine, isoquinoline, diterpene, steroidal alkaloids.