Low frequency of microsatellite instability in hereditary prostate cancer
作者： A.-K. Åhman , B.-A. Jonsson , J.-E. Damber , A. Bergh , H. Grönberg
DOI: 10.1046/J.1464-410X.2001.00104.X
关键词:
摘要: Objective To investigate whether there is widespread microsatellite instability (MSI) in families with hereditary prostate cancer (HPC). Patients and methods Eighty-four tumours from 80 Swedish men 35 HPC were screened for genetic at marker loci BAT-25, BAT-26, BAT-34C4, D2S123 D17S250. Results MSI was detected only five individuals different families. Three (4%) unstable more than two hence classified as high-frequency (MSI-H) according to a previous definition. Interestingly, of the MSI-H patients both familial colon cancer. Conclusions Widespread rare event cancer, indicating that defective DNA mismatch repair not an important element genesis HPC.
sci-hub.se 参考文章(18)
, SM Edwards, SR Lakhani, M Young, C Corbishley, RS Kirby, DP Dearnaley, A Dowe, A Ardern-Jones, J Kelly, RA Eeles, WD Dunsmuir, Allelic imbalance in familial and sporadic prostate cancer at the putative human prostate cancer susceptibility locus, HPC1 British Journal of Cancer. ,vol. 78, pp. 1430- 1433 ,(1998) , 10.1038/BJC.1998.703
A. M. Nystuen, R. B. Terrell, M. B. Cohen, V. C. Sheffield, A. H. Wille, J. C. Cheville, Microsatellite instability in adenocarcinoma of the prostate American Journal of Pathology. ,vol. 147, pp. 799- 805 ,(1995)
Jianfeng Xu, Deborah Meyers, Diha Freije, Sarah Isaacs, Kathy Wiley, Deborah Nusskern, Charles Ewing, Eric Wilkens, Piroska Bujnovszky, G. Steven Bova, Patrick Walsh, William Isaacs, Johanna Schleutker, Mika Matikainen, Teuvo Tammela, Tapio Visakorpi, Olli-P. Kallioniemi, Rebecca Berry, Daniel Schaid, Amy French, Shannon McDonnell, Jennifer Schroeder, Michael Blute, Stephen Thibodeau, Henrik Grönberg, Monika Emanuelsson, Jan-Erik Damber, Anders Bergh, Björn-Anders Jonsson, Jeffrey Smith, Joan Bailey-Wilson, John Carpten, Dietrich Stephan, Elizabeth Gillanders, Isaac Amundson, Tommi Kainu, Diana Freas-Lutz, Agnes Baffoe-Bonnie, Anne Van Aucken, Raman Sood, Francis Collins, Michael Brownstein, Jeffrey Trent, Evidence for a prostate cancer susceptibility locus on the X chromosome. Nature Genetics. ,vol. 20, pp. 175- 179 ,(1998) , 10.1038/2477
Daniel J. Schaid, Stephen N. Thibodeau, David J. Tester, David G. Bostwick, Myra J. Wick, Shannon K. McDonnell, Ailin Shan, Junqi Qian, Robert B. Jenkins, Julie M. Cunningham, Satoru Takahashi, Allelic imbalance and microsatellite instability in prostatic adenocarcinoma. Cancer Research. ,vol. 56, pp. 4475- 4482 ,(1996)
Louis Lacombe, Irene Orlow, Victor E. Reuter, William R. Fair, Guido Dalbagni, Zuo-Feng Zhang, Carlos Cordon-Cardo, Microsatellite instability and deletion analysis of chromosome 10 in human prostate cancer International Journal of Cancer. ,vol. 69, pp. 110- 113 ,(1996) , 10.1002/(SICI)1097-0215(19960422)69:2<110::AID-IJC7>3.0.CO;2-3
J. R. Smith, D. Freije, J. D. Carpten, H. Gronberg, J. Xu, S. D. Isaacs, M. J. Brownstein, G. S. Bova, H. Guo, P. Bujnovszky, D. R. Nusskern, J.-E. Damber, A. Bergh, M. Emanuelsson, O. P. Kallioniemi, J. Walker-Daniels, J. E. Bailey-Wilson, T. H. Beaty, D. A. Meyers, P. C. Walsh, F. S. Collins, J. M. Trent, W. B. Isaacs, Major Susceptibility Locus for Prostate Cancer on Chromosome 1 Suggested by a Genome-Wide Search Science. ,vol. 274, pp. 1371- 1374 ,(1996) , 10.1126/SCIENCE.274.5291.1371
Ronald Honchel, Kevin C. Halling, Stephen N. Thibodeau, Genomic instability in neoplasia. Seminars in Cell Biology. ,vol. 6, pp. 45- 52 ,(1995) , 10.1016/1043-4682(95)90014-4
Xiao‐Ping Zhou, Jean‐Marc Hoang, You‐Jun Li, Raquel Seruca, Fatima Carneiro, Manuel Sobrinho‐Simoes, Ragnhild A Lothe, Catherine M Gleeson, SE Hilary Russell, Françoise Muzeau, Jean‐François Fléjou, Khê Hoang‐Xuan, Rosette Lidereau, Gilles Thomas, Richard Hamelin, None, Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites Genes, Chromosomes and Cancer. ,vol. 21, pp. 101- 107 ,(1998) , 10.1002/(SICI)1098-2264(199802)21:2<101::AID-GCC4>3.0.CO;2-4
Iordanis I. Arzimanoglou, Fred Gilbert, Hugh R.�K. Barber, Microsatellite instability in human solid tumors Cancer. ,vol. 82, pp. 1808- 1820 ,(1998) , 10.1002/(SICI)1097-0142(19980515)82:10<1808::AID-CNCR2>3.0.CO;2-J
Gary D. Steinberg, Bob S. Carter, Terri H. Beaty, Barton Childs, Patrick C. Walsh, Family history and the risk of prostate cancer. The Prostate. ,vol. 17, pp. 337- 347 ,(1990) , 10.1002/PROS.2990170409