Factors influencing surgical outcome in patients with focal cortical dysplasia

作者: S Fauser , T Bast , D-M Altenmuller , J Schulte-Monting , K Strobl

DOI: 10.1136/JNNP.2007.116038

关键词:

摘要: A total of 120 patients with histologically proven focal cortical dysplasias (FCD) were retrospectively analysed for prognostic factors successful epilepsy surgery. Multivariate data analyses showed that older age at surgery, occurrence secondarily generalised seizures and a multilobar extent the dysplasia significant negative predictors. In univariate analyses, longer duration epilepsy, need intracranial EEG recordings incomplete resection FCD which significantly reduced chance becoming seizure free. Histological subtype onset had no predictive value. These findings strongly suggest early consideration surgery in patients.

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