Polymersomes, colloidosomes, liposomes, and other species associated with fluidic droplets

作者: David A. Weitz , Ho Cheung Shum , Daeyeon Lee , Insun Yoon , Jin-Woong Kim

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摘要: The present invention relates generally to vesicles such as liposomes, colloidosomes, and polymersomes, well techniques for making using vesicles. In some cases, the may be at least partially biocompatible and/or biodegradable. formed, according one aspect, by forming a multiple emulsion comprising first droplet surrounded second droplet, which in turn is third fluid, where comprises lipids polymers, removing fluid from e.g., through evaporation or diffusion, until vesicle formed. certain aspects, size of controlled, osmolarity, embodiments, ruptured change osmolarity. contain other species, fluorescent molecules, microparticles, pharmaceutical agents, etc., released upon rupture. Yet aspects are directed methods vesicles, kits involving like.

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