作者: Dean-Mo Liu , Chia-Wei Su , San-Yuan Chen
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摘要: A drug carrier is provided with a structure of lipid shell enclosing aqueous micelles. The includes and emulsifier, in which the emulsifier encloses lipid. components micelles are phospholipids amphiphilic chitosan, enclose an solution containing drug. Furthermore, method preparing also provided. Therefore, pharmaceutical advantages lipid-based nanoparticle included low leakage ability to overcome multiple resistance, this new formulation were further incorporated chitosan featured high payload efficiency. features could enhance intracellular concentration anti-cancer oral bioavailability.