A composition of matter comprising liposomes embedded in a polymeric matrix and methods of using same
作者： Yechezkel Barenholz , Rivka Cohen
DOI:
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摘要: The present disclosure provides a composition of matter comprising liposomes encapsulating in their intraliposomal aqueous compartment at least one active agent, the having diameter 200nm and being embedded water insoluble, absorbed cross-linked polymeric matrix. In embodiment, is held within an medium, preferably iso-osmotic equilibrium with compartments liposomes. also method removal non-encapsulated agent from matter, preparing said pharmaceutical use such matter; providing prolonged delivery to subject need thereof by administering disclosed herein as well package aqueus medium instructions for thereof.
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