In vivo functioning of the Na+, K+-activated ATPase.

摘要: Publisher Summary This chapter discusses the in vivo functioning of Na + , K -activated adenosine-triphosphatase (ATPase). Movement and across plasmalemmal membrane is largely carried out by active energy-dependent mechanisms. Maintaining gradient particularly important view central role commonly played this ion fueling uptake sugars amino acids, control voltage-dependent permeability, exchange for Ca 2+ . Regulation conjunction with to cell volume, proliferation, transcellular movement, maintenance transmembrane electrical potential, controlled release neurotransmitters. In nervous tissue, regulation singular importance because: (1) frequent partial dissipation basal concentration gradients postsynaptic action potentials and, (2) accompanying shifts occurring within relatively restricted extracellular volume may lead significant changes.