Control of angiogenesis by the pericyte: molecular mechanisms and significance.

作者: K. K. Hirschi , P. A.` D’Amore

DOI: 10.1007/978-3-0348-9006-9_18

关键词:

摘要: The microvasculature consists of endothelial cells (EC) with albuminally located pericytes. A number clinical and experimental observations suggest that pericytes contribute to the regulation microvascular growth function. EC appear have a variety means whereby they may influence one another, including soluble factors, gap junctions adhesion molecules, name few. Co-culture systems provided good deal evidence support concept these two interact communications are central vessel assembly, control normal

参考文章(48)
Judah Folkman, Angiogenesis--retrospect and outlook. Experientia. Supplementum. ,vol. 61, pp. 4- 13 ,(1992) , 10.1007/978-3-0348-7001-6_2
N Laver, T N Tillis, W G Robison, J H Kinoshita, M Nagata, Aldose reductase and pericyte-endothelial cell contacts in retina and optic nerve. Investigative Ophthalmology & Visual Science. ,vol. 30, pp. 2293- 2299 ,(1989)
Pfaffenbach D, Engerman Rl, Davis, Cell turnover of capillaries. Laboratory Investigation. ,vol. 17, pp. 738- ,(1967)
Dan J. Crocker, Tariq M. Murad, Jack C. Geer, Role of the pericyte in wound healing: An ultrastructural study☆ Experimental and Molecular Pathology. ,vol. 13, pp. 51- 65 ,(1970) , 10.1016/0014-4800(70)90084-5
I. Otte-Höller, P. Wesseling, D. J. Ruiter, M. M. Verbeek, R. M. W. De Waal, Induction of alpha-smooth muscle actin expression in cultured human brain pericytes by transforming growth factor-beta 1. American Journal of Pathology. ,vol. 144, pp. 372- 382 ,(1994)
J Stone, A Itin, T Alon, J Pe'er, H Gnessin, T Chan-Ling, E Keshet, Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia The Journal of Neuroscience. ,vol. 15, pp. 4738- 4747 ,(1995) , 10.1523/JNEUROSCI.15-07-04738.1995
Thierry C. Gillebert, Stefan G. De Hert, Luc J. Andries, Anton H. Jageneau, Dirk L. Brutsaert, Intracavitary ultrasound impairs left ventricular performance: presumed role of endocardial endothelium. American Journal of Physiology. ,vol. 263, pp. 1- 1 ,(1992) , 10.1152/AJPHEART.1992.263.3.H857
Guillermo de Venecia, Matthew Davis, Ronald Engerman, Clinicopathologic Correlations in Diabetic Retinopathy: I. Histology and Fluorescein Angiography of Microaneurysms Archives of Ophthalmology. ,vol. 94, pp. 1766- 1773 ,(1976) , 10.1001/ARCHOPHT.1976.03910040540013