Troponin assays in the assessment of the equine myocardium

作者: T. M. Rossi , W. G. Pyle , M. G. Maxie , D. L. Pearl , P. W. Physick-Sheard

DOI: 10.1111/EVJ.12209

关键词:

摘要: Summary In 2000, troponin assays were adopted as the test of choice for detection myocardial injury in man. This decision was made after extensive testing and followed a 60 year search biomarker damage with sufficient analytical sensitivity specificity. has led to proliferation use human medicine, each requiring validation before it could be available on open market use. The ever-more analytically sensitive standard reference material continues. adoption veterinary medicine shortly its development man, providing much-needed means detecting monitoring horses. However, application these tests exclusively involved designed clinically validated patients. There is no mandated requirement and, while many have been shown capable equine troponin, wide diversity tests, lack validation, absence protocols their standardisation make problematic. objective this review article address issue, offering guidance where data are encouraging caution there none. Ultimately, overall goal examine critically horse promote accurate appropriate interpretation valid results.

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