Cyclophosphamide-Induced Morphological Changes in Dental Root Development of ICR Mice

作者: Tomomi Kawakami , Yuko Nakamura , Hiroyuki Karibe

DOI: 10.1371/JOURNAL.PONE.0133256

关键词:

摘要: Background Survivors of childhood cancer are at risk late dental development. Cyclophosphamide is one the most commonly used chemotherapeutic agents against in children. The aim this study was to investigate effects cyclophosphamide on root formation molars growing mice and assess morphological changes these roots using three-dimensional structural images.

参考文章(37)
C Goho, Chemoradiation therapy: effect on dental development. Pediatric Dentistry. ,vol. 15, pp. 6- 12 ,(1993)
Bagattoni S, Pession A, Prete A, D'Alessandro G, Piana G, Oral health and dental late adverse effects in children in remission from malignant disease. A pilot case-control study in Italian children. European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry. ,vol. 15, pp. 45- 50 ,(2014)
Ann C. Mertens, Jian Yong, Andrew C. Dietz, Erin Kreiter, Yutaka Yasui, Archie Bleyer, Gregory T. Armstrong, Leslie L. Robison, Karen Wasilewski-Masker, Conditional survival in pediatric malignancies: analysis of data from the Childhood Cancer Survivor Study and the Surveillance, Epidemiology, and End Results Program. Cancer. ,vol. 121, pp. 1108- 1117 ,(2015) , 10.1002/CNCR.29170
ALISON HUTTON, MOIRA BRADWELL, MARTIN ENGLISH, IAIN CHAPPLE, The oral health needs of children after treatment for a solid tumour or lymphoma International Journal of Paediatric Dentistry. ,vol. 20, pp. 15- 23 ,(2010) , 10.1111/J.1365-263X.2009.00999.X
LISBETH BØNLØKKE PEDERSEN, NIELS CLAUSEN, HENRIK SCHRØDER, MALENE SCHMIDT, SVEN POULSEN, Microdontia and hypodontia of premolars and permanent molars in childhood cancer survivors after chemotherapy International Journal of Paediatric Dentistry. ,vol. 22, pp. 239- 243 ,(2012) , 10.1111/J.1365-263X.2011.01199.X
Margareta Näsman, Lars Hammarström, Influence of the antineoplastic agent cyclophosphamide on dental development in rat molars. Acta Odontologica Scandinavica. ,vol. 54, pp. 287- 294 ,(1996) , 10.3109/00016359609003540
Tomomi Kawakami, Yuko Nakamura, Hiroyuki Karibe, Cyclophosphamide inhibits root development of molar teeth in growing mice Odontology. ,vol. 103, pp. 143- 151 ,(2015) , 10.1007/S10266-014-0158-1
David J. Purdell-Lewis, Myrke S. Stalman, Jan A. Leeuw, George B. Humphrey, Huib Kalsbeek, Long term results of chemotherapy on the developing dentition: caries risk and developmental aspects Community Dentistry and Oral Epidemiology. ,vol. 16, pp. 68- 71 ,(1988) , 10.1111/J.1600-0528.1988.TB01845.X