Vitamin b6 derivatives of nucleotides, acyclonucleotides and acyclonucleoside phosphonates

作者: Murali Urlam , Alexander Karpeisky , Shawn Zinnen , Vladimir Y. Vvedensky , Andrei P. Guzaev

DOI:

关键词:

摘要: Compounds, compositions, and methods of using them to treat infections, neoplastic disease, inflammatory pain. Such compounds are nucleotides, acydonucleotides, acydic nucleoside phosphonates (ANP) conjugated with forms and/or moieties Vitamin B6 for delivery past the cell membrane into cell. Methods delivering acydonucleotide ANPs inside by conjugating said B6.

参考文章(62)
Blain Mamiya, Terace M. Fletcher, Sean M. Kerwin, Makoto Wajima, Miquel Salazar, Ira Maine, Shih-Fong Chen, Bradford E. Windle, Methods for modulation and inhibition of telomerase United States Patent and Trademark Office. ,(1997) , 10.26153/TSW/4202
M Tagaya, K Nakano, T Fukui, A new affinity labeling reagent for the active site of glycogen synthase. Uridine diphosphopyridoxal. Journal of Biological Chemistry. ,vol. 260, pp. 6670- 6676 ,(1985) , 10.1016/S0021-9258(18)88832-9
Laurent Gil, Robert N. Young, Rejean Ruel, Yongxin Han, Prostaglandin conjugates for treating or preventing bone disease ,(1999)
Gopal Subramanian, John Gilmore McAfee, Bone-seeking technetium-99m complex ,(1973)
Nicholas D. Kindon, Peter A. Cage, Anthony H. Ingall, N-alkyl-2-substituted ATP analogues and administration to inhibit platelet aggregation ,(1995)
Richard A. Proctor, Paul J. Bertics, Method reducing TNF-alpha in mammals with cerebral malaria ,(1994)
David Rosen, Hanne Bentz, Targeted delivery of bone growth factors ,(1992)