Topical corticosteroids as adjunctive therapy for bacterial keratitis
作者： Samantha Herretes , Xue Wang , Johann MG Reyes
DOI: 10.1002/14651858.CD005430.PUB3
关键词:
摘要: Background Bacterial keratitis is a serious ocular infectious disease that can lead to severe visual disability. Risk factors for bacterial corneal infection include contact lens wear, surface disease, trauma, and previous or eyelid surgery. Topical antibiotics constitute the mainstay of treatment in cases keratitis, whereas use topical corticosteroids as an adjunctive therapy remains controversial. are usually used control inflammation using smallest amount drug. Their requires optimal timing, concomitant antibiotics, careful follow-up.
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M.E. Zegans, T. Lietman, C. Toutain, V. Akki, D. Jayashree, R. Mahalakshmi, M. Srinivasan, V. Moorthy, P. Saine, Analysis of Digital Images of Corneal Ulcers in the Pilot Study for the Steroid Corneal Ulcer Trial (SCUT) Investigative Ophthalmology & Visual Science. ,vol. 47, pp. 1885- 1885 ,(2006)
P.L. Dighiero, J. Gicquel, M. Mercié, Early Use of Amniotic Membrane Transplantation Combined With Topical Steroids in Severe Bacterial Keratitis Investigative Ophthalmology & Visual Science. ,vol. 46, pp. 2767- 2767 ,(2005)
M. Zegans, L. Prajna, T. Lietman, D. Jayashree, N. Acharya, R. Mahalakshmi, J. House, M. Srinivasan, S. Mcleod, J. Whitcher, Steroids for Corneal Ulcers Treatment – SCUT Pilot Study Results Investigative Ophthalmology & Visual Science. ,vol. 47, pp. 4752- 4752 ,(2006)
S. Al-Ghambdi, R. Balabanian, D. Fergusson, W. B. Jackson, J. Blair, Y. I. Pan, W. G. Hodge, G. Mintsioulis, B. C. Lowcock, S. Aaron, Comparison of Antibiotic-Only and Antibiotic-Steroid Combination Treatment in Corneal Ulcer Patients: A Double-Blinded, Randomized Clinical Trial - Interim Report Investigative Ophthalmology & Visual Science. ,vol. 48, pp. 4275- 4275 ,(2007)
Scott M. McClintic, Namperumalsamy V. Prajna, Muthiah Srinivasan, Jeena Mascarenhas, Prajna Lalitha, Revathi Rajaraman, Catherine E. Oldenburg, Kieran S. O'Brien, Kathryn J. Ray, Nisha R. Acharya, Thomas M. Lietman, Jeremy D. Keenan, Visual outcomes in treated bacterial keratitis: four years of prospective follow-up. Investigative Ophthalmology & Visual Science. ,vol. 55, pp. 2935- 2940 ,(2014) , 10.1167/IOVS.14-13980
Kirk R Wilhelmus, Indecision about corticosteroids for bacterial keratitis: an evidence-based update Ophthalmology. ,vol. 109, pp. 835- 842 ,(2002) , 10.1016/S0161-6420(02)00963-6
N. Morlet, D. Minassian, J. Butcher, the Ofloxacin Study Group, Risk factors for treatment outcome of suspected microbial keratitis British Journal of Ophthalmology. ,vol. 83, pp. 1027- 1031 ,(1999) , 10.1136/BJO.83.9.1027
Kenneth F Schulz, David A Grimes, Allocation concealment in randomised trials: defending against deciphering. The Lancet. ,vol. 359, pp. 614- 618 ,(2002) , 10.1016/S0140-6736(02)07750-4
Jay S. Pepose, Kirk R. Wilhelmus, Divergent approaches to the management of corneal ulcers. American Journal of Ophthalmology. ,vol. 114, pp. 630- 632 ,(1992) , 10.1016/S0002-9394(14)74496-4
David J. Parks, Donald A. Abrams, Faith A. Sarfarazi, Harold R. Katz, Comparison of Topical Ciprofloxacin to Conventional Antibiotic Therapy in the Treatment of Ulcerative Keratitis American Journal of Ophthalmology. ,vol. 115, pp. 471- 477 ,(1993) , 10.1016/S0002-9394(14)74449-6