Divergent effects of diltiazem in patients with exertional angina

作者: Kenneth F. Hossack , Robert A. Bruce , Jeffrey B. Ritterman , Fusako Kusumi , Shirley Trimble

DOI: 10.1016/S0002-9149(82)80009-X

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摘要: Fifteen patients with exercise-induced angina were studied at rest and during symptom-limited upright exercise a Swan-Ganz catheter an arterial line in place. Cardiac output was measured using the direct Fick principle. The classified on basis of mean pulmonary capillary pressure maximal exercise. In Group I (eight patients) less than 16 mm Hg II (seven it greater Hg. Patients older heavier had more severe exhibited S-T depression before treatment. Each patient received 120 mg oral diltiazem repeated 1 hour later. both groups duration prolonged (Group I, 5.8 ± 3 versus 6.8 minutes [mean standard deviation], p −5 ,

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