Organic Causes of Erectile Dysfunction in Men Under 40

作者: Wesley Ludwig , Michael Phillips

DOI: 10.1159/000354931

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摘要: There are a significant number of men under 40 who experience erectile dysfunction (ED). In the past, vast majority cases were thought to be psychogenic in nature. Studies have identified organic etiologies 15-72% with ED 40. Organic include vascular, neurogenic, Peyronie's disease (PD), medication side effects and endocrinologic sources. Vascular causes commonly due focal arterial occlusive disease. Young multiple sclerosis, epilepsy trauma close proximity spinal cord at increased risk ED. It is estimated that 8% PD 40, 21% these individuals experiencing Medications causing antidepressants, NSAIDs finasteride (Propecia), antiepileptics neuroleptics. Hormonal sources uncommon young population, however possible Klinefelter's syndrome, congenital hypogonadotropic hypogonadism, acquired hypogonadism. The workup should thorough history physical examination. prevalence vascular prompt consideration nocturnal penile tumescence testing Doppler ultrasound. Treatment options may improve exercise oral PDE-5 inhibitors.

参考文章(51)
Jacques Young, Sylvie Salenave, Sévérine Trabado, Luigi Maione, Sylvie Brailly-Tabard, Male acquired hypogonadotropic hypogonadism: diagnosis and treatment. Annales D Endocrinologie. ,vol. 73, pp. 141- 146 ,(2012) , 10.1016/J.ANDO.2012.03.040
G. Corona, L. Petrone, F. Paggi, F. Lotti, V. Boddi, A. Fisher, L. Vignozzi, G. Balercia, A. Sforza, G. Forti, E. Mannucci, M. Maggi, Sexual dysfunction in subjects with Klinefelter's syndrome. International Journal of Andrology. ,vol. 33, pp. 574- 580 ,(2009) , 10.1111/J.1365-2605.2009.00986.X
Peter Malik, Sexual dysfunction in schizophrenia. Current Opinion in Psychiatry. ,vol. 20, pp. 138- 142 ,(2007) , 10.1097/YCO.0B013E328017F6C4
L. Pan, X. Xia, Y. Feng, C. Jiang, Y. Cui, Y. Huang, Exposure of Juvenile Rats to the Phytoestrogen Daidzein Impairs Erectile Function in a Dose‐Related Manner in Adulthood Journal of Andrology. ,vol. 29, pp. 55- 62 ,(2008) , 10.2164/JANDROL.107.003392
Vincenzo Rochira, Lucia Zirilli, Gabriella Orlando, Daniele Santi, Giulia Brigante, Chiara Diazzi, Federica Carli, Cesare Carani, Giovanni Guaraldi, Premature Decline of Serum Total Testosterone in HIV-Infected Men in the HAART-Era PLoS ONE. ,vol. 6, pp. e28512- ,(2011) , 10.1371/JOURNAL.PONE.0028512
Ricardo Munarriz, Penile Microvascular Arterial Bypass Surgery: Indications, Outcomes, and Complications The Scientific World Journal. ,vol. 10, pp. 1556- 1565 ,(2010) , 10.1100/TSW.2010.153
A Veronelli, A Masu, R Ranieri, C Rognoni, M Laneri, A E Pontiroli, Prevalence of erectile dysfunction in thyroid disorders: comparison with control subjects and with obese and diabetic patients. International Journal of Impotence Research. ,vol. 18, pp. 111- 114 ,(2006) , 10.1038/SJ.IJIR.3901364
Tahir Karadeniz, Medih Topsakal, Ahmet Aydogmus, Dogan Basak, Erectile dysfunction under age 40: etiology and role of contributing factors. The Scientific World Journal. ,vol. 4, pp. 171- 174 ,(2004) , 10.1100/TSW.2004.64
A. F. Radicioni, A. Ferlin, G. Balercia, D. Pasquali, L. Vignozzi, M. Maggi, C. Foresta, A. Lenzi, Consensus statement on diagnosis and clinical management of Klinefelter syndrome. Journal of Endocrinological Investigation. ,vol. 33, pp. 839- 850 ,(2010) , 10.1007/BF03350351