Ultrastructural localization of a fragment (16K) of the common precursor for adrenocorticotropin (ACTH) and β-lipotropin (β-LPH) in the rat hypothalamus
作者： G. Pelletier
DOI: 10.1016/0304-3940(80)90106-8
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摘要: Abstract With an antiserum to a fragment (16K) of the 31K common precursor for both adrenocorticotropin (ACTH) and β-lipotropin (β-LPH), immunohistochemical localization this 16K was performed in rat hypothalamus. At light microscopic level, detected same neuronal cell bodies which also contain ACTH arcuate nucleus. Using serial thin sections immunoelectron microscopy, it has been possible demonstrate that are present not only fibers but dense core vesicles. These results indicated central nervous system is originating from active peptides (ACTH endorphins) stored vesicles and/or its fragment(s).
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