P53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
作者： Carol R. Bradford , Shaobo Zhu , Haruko Ogawa , Tetsuya Ogawa , Matthew Ubell
DOI: 10.1002/HED.10274
关键词:
摘要: Background. A critical factor for successful organ preservation treatment in head and neck cancer may be selecting tumors that respond to chemotherapy radiation. Previous results patients indicated overexpressed p53 were more sensitive than those did not overexpress p53. Methods. To determine the relationship of mutations sensitivity cisplatin vitro, 23 squamous cell carcinoma (HNSCC) lines analyzed sensi-
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