Comparison of GP IIB/IIIA inhibitors and their activity as measured by aggregometry, flow cytometry, single platelet counting, and the rapid platelet function analyzer.

作者: Axel C. Matzdorff , Gitta Kühnel , Bettina Kemkes-Matthes , Reinhard Voss

DOI: 10.1023/A:1012967320220

关键词:

摘要: Background: GP IIb/IIIa inhibitors have primarily been used short-term e.g., during PTCA. They failed to show clinical benefit long-term therapy. One reason might be the absence of a method monitor inhibitor activity. This study compared platelet aggregometry, rapid function analyzer (RPFA) test, single counting, and flow cytometric determination receptor occupancy measure IIb/IIIa-receptor

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