Metabolic Syndrome and Chronic Renal Disease

作者: Vaia Raikou , Sotiris Gavriil

DOI: 10.3390/DISEASES6010012

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摘要: Background: The influence of metabolic syndrome (MetS) on kidneys is related to many complications. We aimed assess the association between MetS and chronic renal disease defined by a poor estimated glomerular filtration rate (eGFR) and/or presence microalbuminuria/macroalbuminuria. Methods: 149 patients (77 males/72 females) were enrolled in study. Chronic was according KDIGO 2012 criteria based eGFR category classified albuminuria. studied as dichotomous variable (0 5 components) including hypertension, waist circumference, low HDL-cholesterol, high triglycerides, glucose. Results: clustering both albuminuria (x2 = 50.3, p 0.001 x2 26.9, 0.003 respectively) found be significant. showed an odds 5.3-fold (1.6–17.8) higher for 3.2-fold (1.2–8.8) combination with diabetes mellitus, which also increased risk 3.5-fold (1.1–11.3). Albuminuria significantly associated glucose 11.8, 0.003, 11.4, 9.1, 0.01 respectively), it mildly HDL-C 5.7, 0.06). A significant triglycerides hypertension 9.7, 0.04 16.1, found. Conclusion: definition impaired function more components rather than evaluation category. may contribute manifestation mellitus.

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