On the Transmission of Alloxan Diabetes and other Diabetogenic Influences

作者: Martin G. Goldner , Gabriel Spergel

DOI: 10.1016/B978-0-12-027306-5.50007-3

关键词:

摘要: Publisher Summary This chapter discusses the transmission of alloxan diabetes and other diabetogenic influences. Pregnancy is best known stress factor that capable inducing carbohydrate abnormalities precipitating mellitus. The incidence manifest in females increases significantly with number pregnancies. However, pregnancy only one a variety environmental stresses may aggravate disease or transform latent form into clinical state. Other such include overfeeding obesity, aging, intercurrent diseases. There cannot be entirely satisfactory interpretation would explain mode induced glucose intolerance. it certain male as transmitting intolerance female, thus, precluding maternal milieu being etiologic. As paramutational process continues, regulator genes involved metabolism become altered some individuals, permitting expression these people, despite normal parents even monozygotic twin.

参考文章(22)
L. Butler, The inheritance of diabetes in the Chinese hamster. Diabetologia. ,vol. 3, pp. 124- 129 ,(1967) , 10.1007/BF01222188
W. R. Waddell, R. A. Field, Carbohydrate metabolism in atherosclerosis. Metabolism-clinical and Experimental. ,vol. 9, pp. 800- 806 ,(1960)
L. Butler, G. C. Gerritsen, A comparison of the modes of inheritance of diabetes in the Chinese hamster and the KK mouse. Diabetologia. ,vol. 6, pp. 163- 167 ,(1970) , 10.1007/BF01212224
ALBERT E. RENOLD, Spontaneous diabetes and--or obesity in laboratory rodents. Advances in metabolic disorders. ,vol. 3, pp. 49- 84 ,(1968) , 10.1016/B978-1-4831-9943-6.50008-6
K. F. Wellmann, B. W. Volk, S. S. Lazarus, P. Brancato, Pancreatic B cell morphology and insulin content of normal and alloxan-diabetic rabbits and their offspring. Diabetes. ,vol. 18, pp. 138- 145 ,(1969) , 10.2337/DIAB.18.3.138
Henry J. John, Diabetes mellitus in children The Journal of Pediatrics. ,vol. 35, pp. 723- 744 ,(1949) , 10.1016/S0022-3476(49)80116-8
George L.A. From, John E. Craighead, Mary F. McLane, Jurgen Steinke, Virus-induced diabetes in mice Metabolism-clinical and Experimental. ,vol. 17, pp. 1154- 1158 ,(1968) , 10.1016/0026-0495(68)90095-4
R. J. Britten, E. H. Davidson, Gene Regulation for Higher Cells: A Theory Science. ,vol. 165, pp. 349- 357 ,(1969) , 10.1126/SCIENCE.165.3891.349
M. S. Gottlieb, H. F. Root, Diabetes Mellitus in Twins Diabetes. ,vol. 17, pp. 693- 704 ,(1968) , 10.2337/DIAB.17.11.693