作者: Martin G. Goldner , Gabriel Spergel
DOI: 10.1016/B978-0-12-027306-5.50007-3
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摘要: Publisher Summary This chapter discusses the transmission of alloxan diabetes and other diabetogenic influences. Pregnancy is best known stress factor that capable inducing carbohydrate abnormalities precipitating mellitus. The incidence manifest in females increases significantly with number pregnancies. However, pregnancy only one a variety environmental stresses may aggravate disease or transform latent form into clinical state. Other such include overfeeding obesity, aging, intercurrent diseases. There cannot be entirely satisfactory interpretation would explain mode induced glucose intolerance. it certain male as transmitting intolerance female, thus, precluding maternal milieu being etiologic. As paramutational process continues, regulator genes involved metabolism become altered some individuals, permitting expression these people, despite normal parents even monozygotic twin.