MDA5/RIG-I and virus recognition.

作者: Osamu Takeuchi , Shizuo Akira

DOI: 10.1016/J.COI.2008.01.002

关键词:

摘要: … responses to influenza A virus infection are governed by a TLR pathway. … and MDA5 recognize different RNA viruses and RNA structures by generating mice deficient in RIG-I and MDA5…

参考文章(48)
Ken Takahashi, Taro Kawai, Himanshu Kumar, Shintaro Sato, Shin Yonehara, Shizuo Akira, Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA. Journal of Immunology. ,vol. 176, pp. 4520- 4524 ,(2006) , 10.4049/JIMMUNOL.176.8.4520
Taro Kawai, Shintaro Sato, Ken J Ishii, Cevayir Coban, Hiroaki Hemmi, Masahiro Yamamoto, Kenta Terai, Michiyuki Matsuda, Jun-ichiro Inoue, Satoshi Uematsu, Osamu Takeuchi, Shizuo Akira, Interferon-|[alpha]| induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 Nature Immunology. ,vol. 5, pp. 1061- 1068 ,(2004) , 10.1038/NI1118
Ken J Ishii, Cevayir Coban, Hiroki Kato, Ken Takahashi, Yuichi Torii, Fumihiko Takeshita, Holger Ludwig, Gerd Sutter, Koichi Suzuki, Hiroaki Hemmi, Shintaro Sato, Masahiro Yamamoto, Satoshi Uematsu, Taro Kawai, Osamu Takeuchi, Shizuo Akira, A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA. Nature Immunology. ,vol. 7, pp. 40- 48 ,(2006) , 10.1038/NI1282
Joao Trindade Marques, Thalie Devosse, Die Wang, Maryam Zamanian-Daryoush, Paul Serbinowski, Rune Hartmann, Takashi Fujita, Mark A Behlke, Bryan RG Williams, A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells. Nature Biotechnology. ,vol. 24, pp. 559- 565 ,(2006) , 10.1038/NBT1205
Bruce Beutler, Celine Eidenschenk, Karine Crozat, Jean-Luc Imler, Osamu Takeuchi, Jules A. Hoffmann, Shizuo Akira, Genetic analysis of resistance to viral infection Nature Reviews Immunology. ,vol. 7, pp. 753- 766 ,(2007) , 10.1038/NRI2174
Daniel B. Stetson, Ruslan Medzhitov, Recognition of Cytosolic DNA Activates an IRF3-Dependent Innate Immune Response Immunity. ,vol. 24, pp. 93- 103 ,(2006) , 10.1016/J.IMMUNI.2005.12.003
Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi, Pathogen Recognition and Innate Immunity Cell. ,vol. 124, pp. 783- 801 ,(2006) , 10.1016/J.CELL.2006.02.015
Kenya Honda, Akinori Takaoka, Tadatsugu Taniguchi, Type I Inteferon Gene Induction by the Interferon Regulatory Factor Family of Transcription Factors Immunity. ,vol. 25, pp. 349- 360 ,(2006) , 10.1016/J.IMMUNI.2006.08.009
A. Pichlmair, O. Schulz, C. P. Tan, T. I. Naslund, P. Liljestrom, F. Weber, C. Reis e Sousa, RIG-I-Mediated Antiviral Responses to Single-Stranded RNA Bearing 5' Phosphates Science. ,vol. 314, pp. 997- 1001 ,(2006) , 10.1126/SCIENCE.1132998