Evaluating the concentration of emamectin benzoate in Atlantic salmon tissues after sea lice treatments

摘要: Abstract Pharmaceutical treatments are an important part of integrated sea lice control strategies in all major salmon producing countries the world. Ensuring that in-feed medication is delivered appropriately, and fish achieve adequate tissue concentration critical to a successful treatment. The muscle emamectin benzoate was assessed post SLICE® treatment 867 Atlantic from 147 treatments. Approximately 90% samples included skin had levels above 60 ng/g (ppb); however, only 63.8% without were at or this threshold. Further, we found wide range concentrations across our samples, with some as high 398 ng/g. variation associated following factors: feeding rate, whether not sample contained skin, year sample, laboratory analyzing tissue, prescribed dose, condition factor, after controlling for temperature, day post-treatment, pen effect. Interestingly, positive relationship between factor dependent on dose feed. In other words, increasing greater effect drug tissues compared low factor. Our findings suggest rate behavior within may be factors consider when applying medicated feed populations ensure more even distribution animals.