Chapter 7. Pulmonary and Antiallergy Drugs

摘要: Publisher Summary Cross-linking of the cell receptors increases membrane permeability, and thereby effects calcium influx. The involvement protein phosphorylation in this process has been suggested present discussion. This chapter reviews understanding production, control IgE its interaction with antigen. reports preparative isolations receptors. It noticed that inability to effectively extrapolate pharmacological behavior newer therapeutic agents observed clinic remains a concern. A review multiplicity corticosteroids on immune processes taken place. class drugs provides effective often essential therapy, although mechanism action allergic disorders uncertain. chromone AA-344 was inhibiting homologous PCA passive systemic anaphylaxis guinea pig, but only slightly Arthus reaction. DSCG ineffective these models. structures major metabolites have described; oxidation at both carbons ethyl substituent; glucuronic acid attachment tetrazole are primary processes. phospholipid methylation stimulate AC by increasing lateral movement activated β-receptor complex providing greater opportunity for coupling enzyme system.