Coordinate Regulation of TET2 and EBNA2 Controls the DNA Methylation State of Latent Epstein-Barr Virus.

作者: Fang Lu , Andreas Wiedmer , Kayla A. Martin , Priyankara J. M. S. Wickramasinghe , Andrew V. Kossenkov

DOI: 10.1128/JVI.00804-17

关键词:

摘要: … shRNA) depletion of TET2 results in a decrease in latency gene expression but can also trigger a switch to lytic gene expression. TET2 … Primer sequences for RT-PCR are listed in Table …

参考文章(58)
KD Robertson, A Manns, LJ Swinnen, JC Zong, ML Gulley, RF Ambinder, CpG methylation of the major Epstein-Barr virus latency promoter in Burkitt's lymphoma and Hodgkin's disease Blood. ,vol. 88, pp. 3129- 3136 ,(1996) , 10.1182/BLOOD.V88.8.3129.BLOODJOURNAL8883129
K. D. Robertson, J. Barletta, D. Samid, R. F. Ambinder, Pharmacologic Activation of Expression of Immunodominant Viral Antigens: A New Strategy for the Treatment of Epstein-Barr-Virus-Associated Malignancies Current Topics in Microbiology and Immunology. ,vol. 194, pp. 145- 154 ,(1995) , 10.1007/978-3-642-79275-5_18
U. Zimber-Strobl, L.J. Strobl, C. Meitinger, R. Hinrichs, T. Sakai, T. Furukawa, T. Honjo, G.W. Bornkamm, Epstein-Barr virus nuclear antigen 2 exerts its transactivating function through interaction with recombination signal binding protein RBP-J kappa, the homologue of Drosophila Suppressor of Hairless. The EMBO Journal. ,vol. 13, pp. 4973- 4982 ,(1994) , 10.1002/J.1460-2075.1994.TB06824.X
B. Kempkes, D. Spitkovsky, P. Jansen-Dürr, J.W. Ellwart, E. Kremmer, H.J. Delecluse, C. Rottenberger, G.W. Bornkamm, W. Hammerschmidt, B-cell proliferation and induction of early G1-regulating proteins by Epstein-Barr virus mutants conditional for EBNA2. The EMBO Journal. ,vol. 14, pp. 88- 96 ,(1995) , 10.1002/J.1460-2075.1995.TB06978.X
Hiroyuki Abe, Atsushi Kaneda, Masashi Fukayama, Epstein-Barr Virus-Associated Gastric Carcinoma: Use of Host Cell Machineries and Somatic Gene Mutations Pathobiology. ,vol. 82, pp. 212- 223 ,(2015) , 10.1159/000434683
Lawrence S. Young, Alan B. Rickinson, Epstein–Barr virus: 40 years on Nature Reviews Cancer. ,vol. 4, pp. 757- 768 ,(2004) , 10.1038/NRC1452
Zhong Deng, Zhuo Wang, Nick Stong, Robert Plasschaert, Aliah Moczan, Horng-Shen Chen, Sufeng Hu, Priyankara Wikramasinghe, Ramana V Davuluri, Marisa S Bartolomei, Harold Riethman, Paul M Lieberman, A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection. The EMBO Journal. ,vol. 31, pp. 4165- 4178 ,(2012) , 10.1038/EMBOJ.2012.266
Anne Woellmer, Jose M. Arteaga-Salas, Wolfgang Hammerschmidt, BZLF1 Governs CpG-Methylated Chromatin of Epstein-Barr Virus Reversing Epigenetic Repression PLoS Pathogens. ,vol. 8, pp. e1002902- ,(2012) , 10.1371/JOURNAL.PPAT.1002902