Combination therapy using active immunotherapy

作者: Toni Weinschenk , Steffen Walter , Norbert Hilf , Niels Emmerich , Harpreet Singh

DOI:

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摘要: The present invention relates to methods of treating cancer in a mammal comprising administering the combination therapy vaccine and multi-kinase inhibitor, wherein comprises an isolated tumor associated peptide having ability bind molecule human major histocompatibility complex (MHC) class-I or class-II. Preferably inhibitor is sunitinib malate and/or sorafenib tosylate pharmaceutically acceptable salt thereof.

参考文章(68)
Toni Weinschenk, Harpreet Singh, Oliver Schoor, Claudia Trautwein, Peter Lewandrowski, Norbert Hilf, Steffen Walter, Composition of tumour-associated peptides and related anti-cancer vaccine ,(2008)
Claudio Thomasin, Giampietro Corradin, Ying Men, Bruno Gander, Hans Peter Merkle, Immunological response potentiation process ,(1994)
Gideon Bollag, John F. Lyons, RAF-MEK-ERK pathway inhibitors to treat cancer ,(2002)