Cancer therapy based on tumor associated antigens derived from cyclin D1
作者： Toni Weinschenk , Harpreet Singh , Steffen Walter
DOI:
关键词: Cyclin D1 、 Medicine 、 Tumor associated antigen 、 Cancer research 、 Cyclin 、 Combination therapy 、 Cancer 、 Immunology 、 Cancer therapy
摘要: The present invention relates to cyclin D1-derived peptides for use in the improved treatment of cancer a patient, particularly form combination therapy using vaccine. Other aspects relate or thereof as diagnostic tool.
lens.org 参考文章(49)
Claudia Lemmel, Steffen Weik, Ute Eberle, Jörn Dengjel, Thomas Kratt, Horst-Dieter Becker, Hans-Georg Rammensee, Stefan Stevanović, Differential quantitative analysis of MHC ligands by mass spectrometry using stable isotope labeling Nature Biotechnology. ,vol. 22, pp. 450- 454 ,(2004) , 10.1038/NBT947
Judith A. McKay, Joy J. Douglas, Val G. Ross, Stephanie Curran, Graeme I. Murray, Jim Cassidy, , Cyclin D1 protein expression and gene polymorphism in colorectal cancer International Journal of Cancer. ,vol. 88, pp. 77- 81 ,(2000) , 10.1002/1097-0215(20001001)88:1<77::AID-IJC12>3.0.CO;2-O
Ylva Hedberg, Estela Davoodi, G�ran Roos, B�rje Ljungberg, G�ran Landberg, Cyclin-D1 expression in human renal-cell carcinoma. International Journal of Cancer. ,vol. 84, pp. 268- 272 ,(1999) , 10.1002/(SICI)1097-0215(19990621)84:3<268::AID-IJC12>3.0.CO;2-8
Anna Karolina Palucka, Hideki Ueno, Joseph Fay, Jacques Banchereau, Dendritic cells: a critical player in cancer therapy? Journal of Immunotherapy. ,vol. 31, pp. 793- 805 ,(2008) , 10.1097/CJI.0B013E31818403BC
Daniel J. Lew, Vjekoslav Dulić, Steven I. Reed, Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast Cell. ,vol. 66, pp. 1197- 1206 ,(1991) , 10.1016/0092-8674(91)90042-W
M Wang, L Sun, J Qian, X Han, L Zhang, P Lin, Z Cai, Q Yi, Cyclin D1 as a universally expressed mantle cell lymphoma-associated tumor antigen for immunotherapy Leukemia. ,vol. 23, pp. 1320- 1328 ,(2009) , 10.1038/LEU.2009.19
S. Gnjatic, D. Atanackovic, E. Jager, M. Matsuo, A. Selvakumar, N. K. Altorki, R. G. Maki, B. Dupont, G. Ritter, Y.-T. Chen, A. Knuth, L. J. Old, Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: Correlation with antibody responses Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 8862- 8867 ,(2003) , 10.1073/PNAS.1133324100
Alexander Buchner, Heike Pohla, Gerald Willimsky, Bernhard Frankenberger, Ronald Frank, Andrea Baur-Melnyk, Michael Siebels, Christian G. Stief, Alfons Hofstetter, Joachim Kopp, Antonio Pezzutto, Thomas Blankenstein, Ralph Oberneder, Dolores J. Schendel, Phase 1 trial of allogeneic gene-modified tumor cell vaccine RCC-26/CD80/IL-2 in patients with metastatic renal cell carcinoma. Human Gene Therapy. ,vol. 21, pp. 285- 297 ,(2010) , 10.1089/HUM.2008.192
Eisei Kondo, Luise Gryschok, Joachim L. Schultze, Michael S. von Bergwelt-Baildon, Using CD40-activated B cells to efficiently identify epitopes of tumor antigens. Journal of Immunotherapy. ,vol. 32, pp. 157- 160 ,(2009) , 10.1097/CJI.0B013E31819031A2
JIANGANG YU, TOMONORI HABUCHI, NORIHIKO TSUCHIYA, EIJIRO NAKAMURA, HIDEAKI KAKINUMA, YOHEI HORIKAWA, TAKAMITSU INOUE, OSAMU OGAWA, TETSURO KATO, Association of the cyclin D1 gene G870A polymorphism with susceptibility to sporadic renal cell carcinoma. The Journal of Urology. ,vol. 172, pp. 2410- 2413 ,(2004) , 10.1097/01.JU.0000138156.24384.16