Risk of Intracranial Hemorrhage From Statin Use in Asians A Nationwide Cohort Study

摘要: Background—Reports of statin usage and increased risk intracranial hemorrhage (ICH) have been inconsistent. This study examined potential associations between the ICH in subjects without a previous history stroke. Methods Results—Patients initiating therapy 2005 2009 ischemic or hemorrhagic stroke were identified from Taiwan’s National Health Insurance database. Participants stratified by advanced age (≥70 years), sex, diagnosed hypertension. The outcome interest was hospital admission for (International Classification Diseases, Ninth Revision, Clinical Modification codes 430, 431, 432). Cox regression models applied to estimate hazard ratio ICH. cumulative dosage quartile adjusted baseline disease score served as primary variable using lowest reference. There 1 096 547 initiators with an average foll...