Influence of age and osteoporosis on calcaneus trabecular bone structure: a preliminary in vivo MRI study by quantitative texture analysis.

摘要: Recent developments in high-resolution MR imaging techniques have opened up new perspectives for structural characterization of trabecular bone by non-invasive methods. In this study, 3-D was performed on 17 healthy volunteers and 6 osteoporotic patients. Two different sequences were used to evaluate the impact acquisition texture analysis results. Images analyzed with four automated methods (grey level histogram, cooccurrence, runlength gradient matrices) enabling quantitative grey intensity distribution within three regions interest (ROI). Texture is not very frequently since interpretation large number calculated parameters difficult. We applied multiparametric data analyses such as principal component (CFA) hierarchical ascending classification (HAC) determine relevant differentiate between sets images (healthy young volunteers, postmenopaused patients). The results suggest that information (depending ROI localization calcaneus) can be extracted from calcaneus osteoporosis age effects structure if strictly same are all patients' examination.