Localization of an actin binding domain in smooth muscle myosin light chain kinase.
作者： Patricia J. Gallagher , James T. Stull
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摘要: Phosphorylation of the regulatory light chain myosin II by myosinlight kinase is important for regulating many contractile processes.Smooth muscle has been shown to be associated withboth actin and filaments in vitro vivo. In this report wedefine an binding region using molecular deletions generaterecombinant mutant proteins that were analyzed co-sedimentation withF-actin. An restricted residues 2-42 animoterminus rabbit smooth wasidentified.
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