The Physiological and Behavioural Adjustments of the Zebrafish 'Danio rerio' Exposed to the β-blocker Propranolol

作者: Kimberly Mitchell

DOI: 10.20381/RUOR-6427

关键词:

摘要: ii Resume iii List of Figures vii Tables x Abbreviations xi Acknowledgements xii CHAPTER 1 General Introduction 1.1. Thesis Rationale 1.2. The Adrenergic System 4 1.2.1. β-Adrenergic receptors 1.2.2. Signal transduction pathways β-ARs 7 1.2.3. adrenergic stress response 8 1.3. β-Blockers 11 1.3.1. Pharmacodynamic properties β-blockers 14 1.3.2. Treatments and side effects in humans 1.3.3. Pharmacokinetics 15 1.3.4. the environment 19 1.3.5. Uptake by fish 24 1.3.6. potential 1.4. Past studies with PROP 29 1.5. Hypotheses 35 1.6. Objectives 37 2: Propranolol Exposure Interferes Adrenoceptor Regulated Processes Zebrafish, Danio rerio 38 2.

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