Nutritional status and cardiac mass and function in children infected with the human immunodeficiency virus.

作者: T L Miller , E J Orav , S D Colan , S E Lipshultz

DOI: 10.1093/AJCN/66.3.660

关键词:

摘要: Malnutrition, skeletal muscle wasting, and changes in cardiac mass function have been described children infected with the human immunodeficiency virus (HIV). This report analyzes relation of nutritional status to HIV-infected children. Thirty-six symptomatic HIV infection underwent simultaneous anthropometric echocardiographic evaluations before antiretroviral therapy or supplemental feedings. Nutritional measurements included weight, height, triceps skinfold thickness, arm circumference. Cardiac left ventricular mass, contractility, end-diastolic dimension, fractional shortening, blood pressure, heart rate. In a cross-sectional analysis, were significantly below age-adjusted standards for height (P = 0.0001), weight thickness 0.001), circumference 0.04). Left normalized body surface area was standard, but contractility normal. Correlation analyses found an inverse between z score (r -0.45, P 0.01), -0.47, 0.006), percentile -0.51, 0.003). An also rate 0.007) -0.46, 0.007). malnourished infection, paradoxical exists mass. The may suggest altered metabolic rates possible increased sympathetic tone.

参考文章(23)
T L Miller, S J Evans, E J Orav, V Morris, K McIntosh, H S Winter, Growth and body composition in children infected with the human immunodeficiency virus-1. The American Journal of Clinical Nutrition. ,vol. 57, pp. 588- 592 ,(1993) , 10.1093/AJCN/57.4.588
Steven E. Lipshultz, E. John Orav, Stephen P. Sanders, Steven D. Colan, Immunoglobulins and Left Ventricular Structure and Function in Pediatric HIV Infection Circulation. ,vol. 92, pp. 2220- 2225 ,(1995) , 10.1161/01.CIR.92.8.2220
P. M. Smythe, A. Swanepoel, J. A. H. Campbell, The Heart in Kwashiorkor BMJ. ,vol. 1, pp. 67- 73 ,(1962) , 10.1136/BMJ.1.5271.67
Brad M. Dworkin, Paul P. Antonecchia, Fred Smith, Lisa Weiss, Marianna Davidian, Dave Rubin, William S. Rosenthal, Reduced Cardiac Selenium Content in the Acquired Immunodeficiency Syndrome Journal of Parenteral and Enteral Nutrition. ,vol. 13, pp. 644- 647 ,(1989) , 10.1177/0148607189013006644
T. J. Lohman, A. F. Roache, R. Martorell, Anthropometric standardization reference manual Medicine and Science in Sports and Exercise. ,vol. 24, pp. 952- ,(1992) , 10.1249/00005768-199208000-00020
M. A. Rossi, J. S. M. Oliveira, S. Zucoloto, O. Pissaia, R. S. Costa, Effect of protein-calorie malnutrition on catecholamine levels and weight of heart in rats. Journal of Neural Transmission. ,vol. 48, pp. 85- 99 ,(1980) , 10.1007/BF01250038
Richard B. Devereux, Daniel R. Alonso, Elizabeth M. Lutas, Geoffrey J. Gottlieb, Emilio Campo, Irene Sachs, Nathaniel Reichek, Echocardiographic assessment of left ventricular hypertrophy: Comparison to necropsy findings American Journal of Cardiology. ,vol. 57, pp. 450- 458 ,(1986) , 10.1016/0002-9149(86)90771-X
Steven D. Colan, Ira A. Parness, Philip J. Spevak, Stephen P. Sanders, Developmental modulation of myocardial mechanics: Age- and growth-related alterations in afterload and contractility Journal of the American College of Cardiology. ,vol. 19, pp. 619- 629 ,(1992) , 10.1016/S0735-1097(10)80282-7
Shyam Sunder Kothari, Tejas M. Patel, Amulyaratha N. Shetalwad, Thakorebhai K. Patel, Left ventricular mass and function in children with severe protein energy malnutrition International Journal of Cardiology. ,vol. 35, pp. 19- 25 ,(1992) , 10.1016/0167-5273(92)90050-D
Steven E. Lipshultz, E.John Orav, Stephen P. Sanders, Kenneth McIntosh, Steven D. Colan, Limitations of fractional shortening as an index of contractility in pediatric patients infected with human immunodeficiency virus. The Journal of Pediatrics. ,vol. 125, pp. 563- 570 ,(1994) , 10.1016/S0022-3476(94)70008-7