T-CELL DEPLETING THERAPIES
作者： Boitano Anthony , Cooke Michael , Mcdonough Sean , Proctor Jennifer Lynn
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摘要: Provided herein are methods of depleting T cells for therapeutic uses, including administration anti-CD2 or anti-CD5 antibody drugs conjugates (ADCs) treatment. ADCs use as agents to treat a stem cell disorder, cancer, autoimmune disease, among other hematological and proliferative diseases. The compositions described can be used deplete populations CD2+ CD5+ cells, such cancer immune also prepare patient hematopoietic transplantation solid organ transplantation.
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