Antimicrobial Susceptibility and Methicillin Resistance in Staphylococcus pseudintermedius and Staphylococcus schleiferi subsp. coagulans Isolated from Dogs with Pyoderma in Japan
作者： Tetsuji KAWAKAMI , Sanae SHIBATA , Nobuo MURAYAMA , Masahiko NAGATA , Koji NISHIFUJI
DOI: 10.1292/JVMS.10-0172
关键词:
摘要: To understand species distribution, trends of antimicrobial susceptibility and prevalence methicillin resistance in canine staphylococci Japan, 190 coagulase-positive (CoPS) were isolated from dogs with pyoderma 2 Japanese veterinary referral hospitals. Using a multiplex polymerase chain reaction (M-PCR) method, two CoPS identified: 170 Staphylococcus pseudintermedius (89.5%) 20 S. schleiferi subsp. coagulans isolates (10.5%). In these isolates, to 7 agents was determined. Overall, the levels cefalexin (CEX), amoxicillin/clavulanic acid (CVA/AMPC), minocycline (MINO), ofloxacin (OFLX), norfloxacin (NFLX), lincomycin (LCM) clindamycin (CLDM) 38.2, 52.4, 34.7, 31.2, 34.1, 1.2 11.2%, respectively. 55% demonstrated CEX, 80% CVA/AMPC, 70% MINO, 45% OFLX or NFLX 30% CLDM. None susceptible LCM. determine methicillin-resistant strains, we used PCR which enabled detection fragment mecA gene 66.5% (113 170) 30.0% (6 20) isolates. The frequencies OFLX, CLDM significantly lower than methicillin-susceptible These data suggest high level Japan.
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T. J. Kim, Y. R. Na, J. I. Lee, Investigations into the basis of chloramphenicol and tetracycline resistance in Staphylococcus intermedius isolates from cases of pyoderma in dogs. Journal of Veterinary Medicine Series B-infectious Diseases and Veterinary Public Health. ,vol. 52, pp. 119- 124 ,(2005) , 10.1111/J.1439-0450.2005.00836.X
Deborah C. Draghi, Stacy Tench, Michael J. Dowzicky, Daniel F. Sahm, Baseline in vitro activity of tigecycline among key bacterial pathogens exhibiting multidrug resistance. Chemotherapy. ,vol. 54, pp. 91- 100 ,(2008) , 10.1159/000118660
H Ito, H Yoshida, M Bogaki-Shonai, T Niga, H Hattori, S Nakamura, Quinolone resistance mutations in the DNA gyrase gyrA and gyrB genes of Staphylococcus aureus Antimicrobial Agents and Chemotherapy. ,vol. 38, pp. 2014- 2023 ,(1994) , 10.1128/AAC.38.9.2014
B. R. Holm, U. Petersson, A. Morner, K. Bergstrom, A. Franklin, C. Greko, Antimicrobial resistance in staphylococci from canine pyoderma: a prospective study of first-time and recurrent cases in Sweden. Veterinary Record. ,vol. 151, pp. 600- 605 ,(2002) , 10.1136/VR.151.20.600
I.S. Mason, M. Kietzmann, Cephalosporins – pharmacological basis of clinical use in veterinary dermatology Veterinary Dermatology. ,vol. 10, pp. 187- 192 ,(1999) , 10.1046/J.1365-3164.1999.00183.X
B J Hartman, A Tomasz, Low-affinity penicillin-binding protein associated with beta-lactam resistance in Staphylococcus aureus. Journal of Bacteriology. ,vol. 158, pp. 513- 516 ,(1984) , 10.1128/JB.158.2.513-516.1984
Y Utsui, T Yokota, Role of an altered penicillin-binding protein in methicillin- and cephem-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. ,vol. 28, pp. 397- 403 ,(1985) , 10.1128/AAC.28.3.397
M. Vanni, R. Tognetti, C. Pretti, F. Crema, G. Soldani, V. Meucci, L. Intorre, Antimicrobial susceptibility of Staphylococcus intermedius and Staphylococcus schleiferi isolated from dogs. Research in Veterinary Science. ,vol. 87, pp. 192- 195 ,(2009) , 10.1016/J.RVSC.2009.01.011
Gregory C. Griffeth, Daniel O. Morris, Jill L. Abraham, Frances S. Shofer, Shelley C. Rankin, Screening for skin carriage of methicillin‐resistant coagulase‐positive staphylococci and Staphylococcus schleiferi in dogs with healthy and inflamed skin Veterinary Dermatology. ,vol. 19, pp. 142- 149 ,(2008) , 10.1111/J.1365-3164.2008.00663.X
Norihisa Noguchi, Takeshi Okihara, Yuta Namiki, Yuichi Kumaki, Yoshihiro Yamanaka, Masaharu Koyama, Kazunori Wakasugi, Masanori Sasatsu, Susceptibility and resistance genes to fluoroquinolones in methicillin-resistant Staphylococcus aureus isolated in 2002. International Journal of Antimicrobial Agents. ,vol. 25, pp. 374- 379 ,(2005) , 10.1016/J.IJANTIMICAG.2004.11.016