Thyroid-Like Follicular Carcinoma of the Kidney in a Patient with Skull and Meningeal Metastasis: A Unique Case Report and Review of the Literature.

摘要: Thyroid-like follicular carcinoma of the kidney (TLFCK) is an extremely rare subtype renal cell with close resemblance to well-differentiated thyroid neoplasms. TLFCK has not been included in 2004 World Health Organization (WHO) classification due limited data available. Only 27 cases have reported literature date. Herein, we report a unique case that presented as striking skull and meningeal metastasis 5 years after initial diagnosis; this first such novel pattern. A 68-year-old woman was found right lesion using computed tomography (CT) during her regular clinical follow-up visit for bladder cancer, but she exhibited no obvious symptoms. The CT scan showed 4.4-cm diameter, slightly lobulated soft tissue mass lower kidney, pathological findings which TLFCK. Five later, patient had progressed metastasis. Both tumor were composed almost entirely follicles dense, colloid-like material resembled carcinoma. However, gland. neoplastic epithelial cells strongly immunoreactive cytokeratin 7 (and vimentin negative transcription factor-1 thyroglobulin. This consist widespread metastases meninges provides evidence variant uncertain malignant potential can be more clinically aggressive than previously believed.