Immune responses during measles virus infection

摘要: The characteristic disease features of measles--fever and rash--are associated with the immune response to infection are coincident virus clearance. MV-specific antibody CD4 CD8 T cell responses generated contribute clearance protection from reinfection. During this same phase activation immunologic abnormalities also apparent. There is a generalized suppression cellular that may increased susceptibility other infections. Autoimmune appear in form acute disseminated encephalomyelitis. If virus-specific inadequate progress pulmonary or CNS manifestations, but without rash. pathogenesis rare SSPE, occurs many years after primary not clear, show measles similar those seen uncomplicated infection.