COVID-19: NEW DISEASE AND CHAOS WITH PANIC, ASSOCIATED WITH STRESS

摘要: COVID-19 (coronavirus disease – 2019) caused by SARS-CoV-2 (also known as 2019-nCoV) is a new infectious etiology, but in manifestations it has some similarities with SARS (Sever Acute Respiratory Syndrome) that ravaged several countries of the world around 2003. Coronaviruses are RNA containing microbes ‘hijack’ mammalian cells to replicate themselves intracellularly, just be released large quantities. first replicates upper respiratory tract, opposed SARS-CoV viruses ‘old’ attack lower tree, especially lungs and cause severe pneumonia. About 80% patients mild, them even asymptomatic only about 10-20% require hospitalization because pulmonary edema rapidly developing bronchopneumonia often leads multiorgan failure, older chronic comorbidities or immunocompromised system (e.g., obesity, diabetes mellitus, cardiovascular diseases).  The overall worldwide mortality 1-2%, genetic variants virus 4-6% mortality, densely populated areas, like Northern Italy, New York city, Spain. In most cases ‘cytokine storm’ (a massive release cytokines) have been described aggravate initial damage heart. Epidemiologically, true incidence prevalence COVID-19, likely, will never uneven testing for viral and/or developed IgM IgG antibodies against virus. From public health perspectives, hardest hit areas those were not prepared, had poorly organized underfunded service, did follow preventive measures such social distancing, isolation frequent hand washing. poor organization services, if associated denial rapid spread lead chaos, panic and, predictably, sever distress many people